Due to the short size of the probes and the consistent melting temperature range, these probes are able to efficiently cross cell barriers and bind to their intended target. myTags improve experimental results by reducing non-specific hybridization and background signal which typically occur with traditional BAC catalog probes.
Labeled myTags probes are delivered ready-to-use at a minimum yield of 500pmol of single-stranded DNA. The probes can be single- or triple-labeled with a fluorophore of choice, and we can assist in selecting compatible fluorophore combinations for multi-color FISH or other applications requiring multiple fluorophores. If a desired labeling option is not listed in our standard offering, please contact us for availability.
We offer free assistance in designing probes or can incorporate self-designed probes into the myTags labeling system. myTags FISH probes have been successfully used in specialized applications including 3D DNA-FISH, Cryo-FISH, and RNA-FISH in a variety of cell types.