iGEM Team Sponsorship
The International Genetically Engineered Machine (iGEM) competition is the largest competition of students in the field of synthetic biology. Every Spring since 2004, interdisciplinary teams from all over the world are formed who design and build biological systems that address a pressing environmental, scientific or societal need. They all have one goal, receiving one the Gold Medals at the Giant Jamboree held in Boston, MA in October.
Arbor Biosciences identifies with the hard work, passion and heart that all participating students put into their projects. By connecting with young professionals training to be the next generation of scientists and innovators, we recognize their commitment to improve and develop the scientific world.
Special Offer for ALL registered iGEM 2019 Teams*
All teams participating in the iGEM 2019 competition will receive a special iGEM 50% discount on orders of eligible products, which includes the myTXTL® and myNGS Guides™ product lines. Please submit promo code #iGEM2019AB along with your team name, when inquiring for a quote or submitting an order.
*Discount is available until October 1st, 2019 (11:59 PM EST). Terms and conditions apply.
Products Eligible for iGEM 2019 Promotion:
myTXTL®– Cell-Free Expression System
myNGS Guides™ – CRISPR-Powered NGS
We were excited to attend the Giant Jamboree on October 31 – November 4, 2019 in Boston at the Hynes Convention Center to meet with all of the participants and chat about synthetic biology .
2019 Sponsored Teams
We were proud to support the following iGEM Teams in the 2019 competition with our versatile myTXTL® Cell-Free Expression platform and myNGS Guides® sgRNA pools. Visit their team pages to learn more about their thrilling projects.
Team: TU DRESDEN
Project: DipGene – Designing a gene-sensitive Paper-strip
We aim to provide a fast and easy tool for detecting any nucleic acid sequence of interest from microbial samples and human cells. By combining a novel DNA extraction method with a newly designed fusion protein, it will be possible to obtain a visual color readout within minutes, which will indicate the presence or absence of our sequence of interest. Target sequence binding is performed by RNA guided nucleases, based on the CRISPR/Cas9 mechanism. The method will be designed to be in the field applicable, this means, it will be cheap, fast and less technology dependent. Ideally it will not even require electricity. By doing so, we will be able to open a new scope of diagnostic application to a broad audience.
Our project focusses on Xylella fastidiosa, a plant pathogen that causes disease in more than 100 different host plants. Xylencer is an enhanced bacteriophage therapy, that aims to use the insect that spreads Xylella fastidiosa to spread the cure and works together with the host plant to combat Xylella fastidiosa. On top of this, we strive to develop a fully automated detection system that detects presence of X. fastidiosa in the insect vectors.
Team: CU iGEM
Project: Biological Water Desalination
CU iGEM team aims to tackle the water shortage problem by developing biological desalination systems using two approaches. The first is to genetically engineer Debaryomyces hansenii by introducing osmoprotectant and symporter genes to increase its ability to accumulate salts, especially sodium chloride. The second approach is a cell-free one, where proteins produced by a cell-free system bind to sodium and chloride ions, and then separated from the water.
The aim is to provide an eco-friendly and cost-effective desalination solution, and to showcase the versatility of the synthetic biology in water applications.
Project: Mycolactone Diagnostics
The iGEM Team BOKU-Vienna is addressing an urgent medical issue this year, as they are aiming to develope an easy-to-use, affordable and reliable diagnostic method for the neglected tropical disease Buruli ulcer. The approach comprises the specific binding of the accountable toxin – Mycolactone – to an aptamer sequence, which activates a toggle switch that finally results in the simple outcome of a colour change, indicating the presence of the pathogen, Mycobacterium ulcerans.
Team: NUS Singapore
Project: E. coLIVE
While engineered bacteria are very promising as a tool for applications like bio-manufacturing and therapeutics, their limited life span and inability to function as a closed system are major constraints to their usage. We at NUS aim to manipulate the life cycles of bacteria, providing fine control over the metabolic activity of the cell. Our overall goal is to lengthen the time the cells are capable of protein production, thereby improving the viability of future cell-based production systems.
Project: MEDEA: Machine – Enhanced Directed Evolution of Aptamers
The goal of our team is to create an innovative and affordable way to synthesize novel aptamers: the directed evolution of aptamers guided by in silico design. Our genetic system will introduce random mutations in a known aptamer and select the ones with the most effectiveness regarding their ability to bind to the target molecule. The initial sequence of the aptamer will be designed using bioinformatic systems. Subsequently, our mechanism will allow small laboratories and biotechnology teams, with no access to expensive equipment, to design their own aptamers, which hold great promise in medicine, industry and agriculture.
The GIFU_TOKAI team seeks to enable protein mass production in cell-free systems through gene expression from circularized RNA. The team is trying to invent a new method for protein expression by repeating Translation coupling on circular RNA.
Team: ETH Zurich
Project: Libraries for Personalized Phage Therapy
Antibiotic resistances are one of the biggest threats to global health, food security and development of our society today. Phage therapy is an alternative method to treat bacterial infections, but the screening and engineering of phages specific to new targets remains a challenge. Our project aims to develop a system for the efficient generation of phage libraries that allow rapid identification of phages specific to a pathogenic bacterium isolated from a patient.
Project: A.D.N. : Airborne Detector for Nucleic Acids
A.D.N., or Airborne Detector for Nucleic Acids, aims at improving air quality control in environments such as hospitals and nursing homes by creating an all-in-one and easy-to-use device to collect and detect human viral pathogens in the air. Using riboregulatory elements called Toehold switches as a detection method, our instrument is designed to recognize specifically the poxvirus (chickenpox), the norovirus (gastroenteritis) and the measles virus. Our project will help further the knowledge on aerial viral transmission in epidemic context and will be a cornerstone in implementing air quality control procedures to prevent theses potentially deadly nosocomial infections.
Does your iGEM project require a cell-free system or a pool of custom guide RNAs for your project? Please contact us to explore the possibilities!