myReads® – NGS Services for Targeted Sequencing

The myReads® services team at Arbor Biosciences is ready for your NGS target capture project.

We offer competitively-priced services for library preparation and target capture using our myBaits kits coupled with sequencing on any of the NGS platforms. In collaboration with you, we will assist in selecting the most appropriate project configuration to accommodate the research goals, sample quality, and budget of your project. We accept NGS target capture projects from any organism and pair with with one of the myBaits target capture panels, including custom, ultraconserved elements (UCEs), or whole genome enrichment (WGE).

The myReads group of seasoned scientists have decades of collective experience with planning and executing custom NGS target capture projects, including a wide range of novel applications and working with difficult specimens such as ancient and museum DNA. Our team has utilized an efficient and robust system to process hundreds of projects and thousands of client samples through successful library preparation, capture, and sequencing.

To initiate a project or obtain an estimate, please contact us with details on the number of samples, quality of your samples’ DNA, and a description of your overall research goals. Our scientific experts can recommend appropriate parameters for any project and accommodate most specific preferences for configuration options such as library construction methods, capture conditions, and sequencing parameters to maximize data output from the project. Learn more below about the myReads process and how to submit a project proposal.

Features & Benefits

Proven system
Consistent results from high-complexity NGS library preparation
Fast turn-around
From DNA to sequence data in weeks
Multiple sample types
Utilize fresh, degraded, metagenomics, or even ancient DNA
Collaborative process
Design consultation to meet project budget and goals
Multiple Sequencing Platforms
Select from Illumina, Ion Torrent, PacBio
Volume discounts
Tiered per-sample pricing for larger projects

Our goal is to provide NGS service for your project as if you were working directly with one of your research collaborators. We strive for a transparent and cooperative approach to NGS projects, and will communicate openly with you to find the right solution for your individual research design needs. We have decades of collective experience in molecular biology, including target capture & high-throughput sequencing, and working with difficult specimens.

In order to facilitate transparent, collaborative projects, we have opted to not offer specific guarantees for target capture & sequencing service projects, since every custom project is completely unique. In science, sometimes research projects do not go 100% according to plan. However, you will only pay for the services that we actually perform. We will give every project our individual attention, and all laboratory work is performed by hand on the bench by our team of dedicated & experienced researchers. Our goal is to provide you with the very same dedicated laboratory attention that you & your research team would give to your own work. You can be assured that we will communicate openly with you about all aspects of your project, and will not commit to a project before first discussing all the options with you.

We offer a full suite of services for next-generation sequencing projects, on both regular specimens as well as degraded specimens such ancient DNA including:

  • Library preparation for Ion Torrent, Illumina, and PacBio
  • Target enrichment using myBaits catalog and custom kits
  • High-throughput sequencing on Ion Torrent, Illumina, and PacBio instruments


Figure 1. Demonstration of a range of customizable NGS library insert size options available from myReads NGS services. Arbor Biosciences can help you to choose the best average insert length appropriate for your specific myBaits target capture project, whether SNP resequencing, exon capture, UCE sequencing, or more. Depending on the quality of your DNA, the nature of your desired target regions, and your planned sequencing platform and read protocol, your project may benefit from either shorter or longer NGS library sizes.

We currently do not offer DNA extraction as a standard service option. However, we do have the facilities and expertise for performing DNA extraction on both regular and degraded specimens. Therefore, we may be able to offer this for your project, depending on the circumstances. Please contact us directly to inquire about special service options.

We offer NGS service on any type of non-hazardous DNA extract, whether from high-quality or degraded specimens. However, your samples should still meet our standard submission requirements for your type of service project, including relevant negative controls where applicable. Otherwise, your samples may be unable to pass our quality controls, or your project could be delayed. Please note that currently we are not accepting projects on human ancient DNA specimens for target capture of human DNA.

myReads Sample Submission Form [.XLSX]

The guidelines in our Sample Submission Form should be sufficient for most standard DNA extracts derived from fresh, high-quality, relatively recent genomic DNA specimens (e.g. DNA extracted from fresh, frozen, or alcohol-preserved tissues).

In addition, we are currently accepting most service projects for atypical or sensitive samples, including specimens with degraded or rare targets (e.g., ancient DNA, museum, archival, metagenomic, environmental, etc). However, you should first contact us with more information about your samples & research goals, so that we can determine if we are able to accept your project. We may provide you with a customized set of sample submission requirements that are tailored for your particular application.

Due to the inherently variable nature of target capture & high-throughput sequencing experiments (especially for new, untested, custom baitsets), we are unable to offer service guarantees related to turnaround time, unique read sequencing coverage depth, on-target percentage, and other experimental outcomes.

In order to facilitate transparent, collaborative projects, we have opted to not offer specific guarantees for service projects, since every custom project is completely unique. In science, sometimes research projects do not go 100% according to plan, and for target capture, it is very difficult to plan for specific sequencing outcomes without prior experimental data. However, you will only pay for the services that we actually perform, and we will not accept a project before discussing all the options with you.

You will receive updates and estimated timelines for completion of different stages of your project. If you are working within a specific deadline, we will certainly make every effort to accommodate that, though we cannot guarantee that it will be possible to finish your project within that window.

We would prefer that we make the libraries so that we have direct control over the uniformity and quality of the libraries going into target capture. However, yes, you can provide us directly with libraries that you make yourself. Please confer with us to make sure that we are fully aware of the type of libraries that you are using, since it is critical to choose the correct adapter-specific blocking oligos during capture and the right amplification primers after capture.

Yes, absolutely. We typically have enough material to perform multiple different types of captures from a single set of libraries that we generate. Please contact us for more information about pricing for your individual project configuration needs.

Team Expertise

  • Design Services
  • Collaborations
  • Project Management