A targeted approach to microbial genome sequencing

Many biological sample types are dominated by DNA from other sources, requiring significant next-generation sequencing (NGS) depths to resolve specific microbial genomes or to fully characterize the variation within microbial communities. Targeted sequencing that excludes background non-target DNA from samples prior to NGS solves this problem and dramatically reduces the overall costs of sequencing and data analysis per sample. Hybridization capture is the most versatile technique for comprehensive, cost-effective targeted NGS of both viruses and bacteria in complex samples.

Daicel Arbor Biosciences enables researchers to achieve the full benefit of targeted microbial sequencing with solutions for hybridization capture that offer:

High adaptability, enabling whole genome or complex gene family sequencing from any virus or bacteria.
Greater sequencing depth, enabling 100-fold or higher enrichment of microbial genomes from biological samples.
Significant cost savings by sequencing only target genes/genomes of interest.
Flexibility to sequence almost any sample type, from cell culture, tissue, saliva, fecal, or environmental collections.
Broad applications, including 16S rRNA, metagenomics, and whole genome sequencing.

Want a comprehensive solution for targeted or whole-genome microbial sequencing? Check out our customized Sequencing and Bioinformatics services.

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