A targeted approach to comparing genomic sequences within or between species

Next-generation sequencing (NGS) provides the genomic sequencing breadth and depth necessary for phylogenetic analyses. Pairing NGS with target capture technology can greatly increase discovery efficiency. The flexible nature of hybridization-based target capture technology can tolerate multiple nucleotide sequence mismatches between the synthetic capture probe and the target NGS library molecule. This simple yet critical principle has turned NGS-based sequence capture into a powerful tool for variant discovery and evolutionary and phylogenetic research.

Daicel Arbor Biosciences enables evolutionary biology researchers to maximize their efficiency with hybridization capture solutions that offer:

The ability to recover unknown variation on the scale of hundreds, thousands, or even tens of thousands of genomic loci—ideal for high-resolution phylogenetics among both closely and distantly related individuals.
Favorable recovery from a variety of sample sources, including degraded or ancient samples.
Flexibility and scalability for any size project, allowing accurate sequencing of hundreds or thousands of samples and loci at once.
Cost-effectiveness, without requiring large upfront orders to achieve feasible per-sample costs.

Want a comprehensive solution for targeted or whole-genome sequencing? Check out our customized Sequencing and Bioinformatics services.

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