In cell-free protein expression systems, gene transcription (TX) and translation (TL) are unbound from constraints required for cell culture-based processes. myTXTL systems offer a versatile and easy-to-use cell-free expression platform for protein synthesis, enzyme engineering, and synthetic biology processes in industry and academia.
Our cell-free myTXTL systems allow rapid and parallel production of soluble or toxic proteins and other complex biological structures, like bacteriophages, under open-reaction conditions. This enables easy manipulation, addition of chaperone molecules and straightforward downstream processing of synthesized proteins, enzymes and phages.
Accelerate your workflow with cell-free protein expression tools that let you screen more variants in less time. Accomplish in two days what would take 3 weeks with in-vivo methods.
Scale up production with high-throughput solutions that enable increased yield with reliable performance.
Achieve superior results with tools designed for ease of use, backed by scientific experts available to help optimize your protocols and ensure your success.
Perform protein expression not possible with in-vivo methods, such as synthesizing toxic proteins that prevent cell survival.
myTXTL utilizes the endogenous gene transcription (TX) and translation (TL) machinery derived from E. coli where gene expression is initialized by simply adding a nucleotide template—DNA or RNA—to the master mix and detecting recombinant proteins after only a few minutes.
Based on a system originally developed by Prof. Vincent Noireaux at the University of Minnesota, our revolutionary TX-TL technology has been further refined by Daicel Arbor Biosciences for greater robustness to deliver reliable, consistent performance.
myTXTL has been employed for various applications in protein engineering and synthetic biology research, including the following:
- Synthetic biology for bacteriophage research
- Prototyping of gene circuits
- Bio-pharmaceuticals for drug discovery using microbiome engineering
Our scientists are ready to help you select the right Daicel Arbor Biosciences product for your research needs.