Custom Probe Design

Our experts will apply our advanced proprietary probe design algorithms to craft a custom probe design for your targeting needs, for any organism or application. Our scientific team has decades of experience designing custom probes for a wide variety of applications, including multi- or single locus/gene localization, chromosome painting, chromosomal indexing/barcoding, haplotyping, and more.

Only the highest specificity regions with minimal background noise and cross-reactivity for premium performance in any downstream experimental application would be selected for the probe design.

And with our transparent and straightforward scientific communication process, you always have full control and ownership over the oligo sequences for each and every myTags Custom probeset.

Oligo Synthesis

For standalone orders and/or complex probe designs requiring up to 100K+ oligos, our Single Synthesis option provides maximum value. For smaller and/or multiple designs, our new Indexed Synthesis option maximizes both flexibility and cost-effectiveness.

Regardless of the synthesis approach used, all unique probesets are delivered individually and include individual final probeset pool composition verification via next-generation sequencing.

You can choose to receive your individual probe pool(s) either as immortal amplifiable substrate(s) ready for labeling, or pair with our flexible Labeling Service to receive ready-to-use probes for your experiments.

The proprietary oligo synthesis technology from Daicel Arbor Biosciences enables parallel synthesis of tens of thousands of different probe sequences simultaneously. These oligos are provided in a single pool for use in a variety of downstream (F)ISH configurations. Arbor can provide oligo pools of any scale, up to hundreds of thousands of oligos for large-scale painting applications. Single Synthesis is the new name for the former myTags Immortal or myTags Labeled oligo pools.

As pool amplification technologies advance, we’ve enhanced the efficiency of your myTags oligo pool order by adding optional custom indexes during synthesis that enable us to subsequently subdivide the pool (“deconvolution”). This allows us to offer the maximum flexibility for experiments benefiting from multiple smaller probe sets, such as the localization of small genome or transcriptome targets.

Labeling Services

To better suit YOUR experimental needs, we now offer labeling as a service for our wide range of fluorescent and non-fluorescent label options, which can be applied to any of our upstream immortal pool synthesis products. This enables maximum flexibility to meet your dynamic research needs, such as the same probe oligos in multiple colors/tags or a new color/tag of a previously-ordered design.

Our new Labeling Service pairs perfectly with our new Indexed Synthesis options (described above) to create a fully custom, ready-to-use toolkit for your complex genome/transcriptome visualization projects.