NGS Platform Support
…data, we can configure a sequencing design that is right for your research goals and budget. Combining our Sequencing service with our Library Preparation, Targeted Sequencing, DNA/RNA Extraction, and Bioinformatics…
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Variability in cell-free expression reactions can impact qualitative genetic circuit characterization
…titrations of seven genetic circuits of increasing complexity using reaction conditions that ostensibly follow the same protocol but vary by person, instrument and material batch. Although the raw activities vary…
Long-read sequencing
…custom-designed probes in flexible enrichment kits that are compatible with multiple NGS workflows, including sequencing on most short- and long-read platforms Want a comprehensive solution for targeted or whole-genome sequencing?…
International Plant & Animal Genome XXVIII in San Diego, CA. Focus: NGS
…sites, respectively. The broad range of adaptability of RGEN-ISL to different temperatures and combinations of methods has the potential to advance the field of chromosome biology. Complete Wheat Exome Analysis…
Terrestrial mammal surveillance using hybridization capture of environmental DNA from African waterholes
…using DNA from non-African mammals showed that baits covering 30% of non-target mitogenomes produced 91% mitogenome coverage after capture. In the mock samples, over-representation of DNA of one species still…
Ancient DNA From Museum Specimens and Next Generation Sequencing Help Resolve the Controversial Evolutionary History of the Critically Endangered Puebla Deer Mouse
…mitogenomes, our results revealed that P. mekisturus forms a well-supported distinct lineage outside the clade containing all other members of the Peromyscus melanophrys group. Additionally, the mitogenome phylogeny further supports…
Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes
…mitogenomes and 815 modern mitochondrial control region sequences from across South America. In addition, we performed osteometric analyses to differentiate big and small body size camelids. A comparative analysis of…
Population genetics of two chromatic morphs of the Chagas disease vector Rhodnius pallescens Barber, 1932 in Panamá
…conducted with regards to the population structure and dispersal potential of Triatominae vectors, particularly in R. pallescens. Next generation sequencing methods such as RADseq and complete mitochondrial DNA (mtDNA) genome…
High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study
…and compared to 141 nonvaccinated control cases. Autopsies were performed on 16 partially and 13 fully vaccinated individuals. Most patients were elderly and suffered from several relevant comorbidities. Real-time RT-PCR…
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health, we designed mosaic nanoparticles that present randomly arranged sarbecovirus spike…
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