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Xist nucleates local protein gradients to propagate silencing across the X chromosome
…genes is unknown. We show that Xist foci are locally confined, contain 2 RNA molecules, and nucleate supramolecular complexes (SMACs) that include many copies of the critical silencing protein SPEN….
Evolution 2022. Focus: myBaits
…variable diversification rates. BMC Biology, 20(1), 75. Stoek, F., Barry, Y., Ba, A., Schulz, A., Rissmann, M., Wylezich, C., Sadeghi, B., Beyit, A. D., Eisenbarth, A., N’diaye, F. B., Haki,…
Extended kinship analysis of historical remains using SNP capture
…kinship from very low-coverage sequencing data. Reference: Gorden, E.M., E.M. Greytak, K. Sturk-Andreaggi, J. Cady, T.P. McMahon, S. Armentrout, & C. Marshall. (2022). Extended kinship analysis of historical remains using…
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Super-resolution imaging reveals distinct chromatin folding for different epigenetic states
…megabases, which encompasses the sizes of genes, gene clusters and regulatory domains, the three-dimensional (3D) organization of DNA is implicated in multiple gene regulatory mechanisms, but understanding this organization remains…
Meiotic crossovers characterized by haplotype-specific chromosome painting in maize
Abstract Meiotic crossovers (COs) play a critical role in generating genetic variation and maintaining faithful segregation of homologous chromosomes during meiosis. We develop a haplotype-specific fluorescence in situ hybridization (FISH)…
Anchored Phylogenomics, Evolution and Systematics of Elateridae: Are All Bioluminescent Elateroidea Derived Click Beetles?
Click-beetles (Coleoptera: Elateridae) are an abundant, diverse, and economically important beetle family that includes bioluminescent species. To date, molecular phylogenies have sampled relatively few taxa and genes, incompletely resolving subfamily…
Helical coiling of metaphase chromatids
Chromatids of mitotic chromosomes were suggested to coil into a helix in early cytological studies and this assumption was recently supported by chromosome conformation capture (3C) sequencing. Still, direct differential…
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