These genes were described in two major studies: Kandoth et al 2013 “Mutational landscape and significance across 12 major cancer types” (Nature 502:333-339, doi:10.1038/nature12634) and Lawrence et al 2014 “Discovery and saturation analysis of cancer genes across 21 tumour types” (Nature 505:495-501, doi: 10.1038/nature12912). The panel targets ~1.5Mb of total sequence from 290 genes indentified between the two studies for their roles in cancer. The panel is an excellent, cost-effective choice for exploratory targeted exome sequencing in a variety of research contexts. myBaits kits are provided as a complete solution for targeted sequencing including buffers, bait sets and blockers specific to the NGS library prep of choice.
- Predesigned – Optimized performance for oncology research
- Comprehensive – Pan-cancer panel targeting 1000s of exons from 100s of genes
- Curated – Loci chosen from major cancer field publications
- Cost-effective – Lower per-reaction price than whole genome or exome sequencing