…and indirectly the abundance of the tracr-CRISPR RNA. We identify a widely conserved CvkR binding motif 5’-AnnACATnATGTnnT-3’. Crystal structure of CvkR at 1.6 Å resolution reveals that it comprises distinct…
Old World lupins constitute an interesting model for evolutionary research due to diversity in genome size and chromosome number, indicating evolutionary genome reorganization. It has been hypothesized that the polyploidization…
The main objective of this project was to generate a large single nucleotide polymorphism (SNP) marker resource for later saturation of the genetic linkage map and fine mapping of quantitative…
An incomplete carcass of an extinct bison, Bison ex gr. priscus, was discovered in 2012 in the mouth of the Rauchua River (69°30′N, 166°49′E), Chukotka. The carcass included the rump…
…different non-tuberculous mycobacteria and culture-negative for tuberculosis were used as controls in the qPCR assays and pre-sequencing runs. Additionally, 780 clinical isolates in the region of Comunidad Valenciana (Spain) were…
…guide the search for effective treatments by ruling out those that lack efficacy in vivo. Remdesivir (GS-5734) is a nucleotide analogue prodrug with broad antiviral activity1,2 that is currently being…
…when and where they originated and were distributed during the 20th century, remains unclear stressing the need for One Health focused research. Accordingly, we conducted a time-scaled molecular epidemiological reconstruction…
…findings concur with previous research in suggesting that O. psammophila and O. harringtonii are nested within a paraphyletic Oenothera cespitosa . By contrast, our results show clearly that the two…
The 5S and 45S rDNA sites are useful chromosome landmarks and can provide valuable information about karyotype evolution and species interrelationships. In this study, we employed fluorescence in situ hybridization…
…Nature regarding the evolution of immune genes due to the Black Death. The research uses myBaits target sequencing to study hundreds of immune loci from human ancient DNA samples. https://www.nature.com/articles/s41586-022-05349-x…
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