The custom bioinformatics service process begins with a consultation to understand your research goals and project requirements. Our team of experts then provides tailored solutions, including customized data analysis pipelines, software development, and consulting services, to meet your specific needs. The final results are delivered in a timely and reliable manner, providing you with actionable insights to support your research.

Many sample types and species will require special permits for shipping internationally (or domestically). We can provide some advice, but ultimately you are responsible for proactively identifying the permit(s) that are required for your unique samples. Some examples of biological samples that require permits are tissue or DNA from CITES-listed specimens and plant tissues regulated by the USDA/APHIS.

If Daicel Arbor Biosciences is required to apply for an import permit on your behalf, you will be required to pay a permit application fee, regardless of whether the application is successful.

We strongly encourage our customers to research shipping regulations before contacting us about your project to determine your specific permit needs. Incorrect or incomplete documentation may result in the seizure and loss of your samples at Customs, and potentially the assignment of fines/fees.

The timeline for results will depend on the complexity and scale of the project. As our clients often work under tight timelines, we are adept at expediting processes in the most efficient manner possible. Our team of experts will work with you to establish a timeline that meets your needs and ensures timely delivery of results.

Yes. We require documentation that all relevant and necessary ethics approvals have been granted for any human specimens that you would like us to work on. This includes both contemporary and ancient samples and includes both tissue and nucleic acid derivatives. Please contact us to receive our Ethics Statement document if you are interested in sending human samples to us. We do not accept clinical specimens and are not CLIA-certified.

Our team of experts uses state-of-the-art algorithms and computational methods to deliver high-quality, reliable results. During our upfront consultation, our goal is to find the most appropriate pipeline match for your research goals and project configuration. We perform quality control checks and validation throughout the bioinformatics analysis process to ensure that our results are accurate and trustworthy. We are available for support and consultation prior to, during, and after a project to answer any technical questions.

We prepare short-insert libraries with 8-bp unique dual indexes.

We prepare long-insert libraries with 16 bp identical dual indexes.

Our standard deliverable consists of a comprehensive project report that outlines our methodology, workflow, tables, and figures. We can also tailor our deliverables to your preferences, such as intermediate files, customizing figures and tables.

Our library preparation protocols have been carefully tested and optimized for both WGS and targeted sequencing applications. We have protocols that are appropriate for a wide range and variety of input qualities and quantities that have been successfully applied to thousands of samples. Therefore it is very likely that one of our existing protocols will work well for your application, but if you have very specific project constraints, our NGS experts would be happy to discuss the options with you.

Likely yes. Our team of scientists at Daicel Arbor Biosciences come from a range of scientific backgrounds and possess expertise in diverse applications, data analysis workflows and bioinformatics tools. It is likely that our team members have experience working with datasets and analyses that are comparable to yours, and they have a proven track record of effectively handling projects applicable to a diverse range of research fields, such as agrigenomics, non-model organism genomics, functional genomics, phylogenetics/phylogenomics, genotyping, degraded or ancient DNA, and more.

Upon arrival, we will take a look at your shipment and plastics to ensure that the samples have not been damaged during their journey. At that point, your project will enter our QC queue.

For Standard and Long Insert quality DNA samples, we will quantify the total gDNA with a spectrofluorometric assay, purify up to 80% of the material, and re-quantify the samples. For Degraded quality DNA samples, we will perform the initial total gDNA quantification as well as visualize at minimum a subset of your samples on the Agilent TapeStation platform. For Ancient quality DNA samples, we will perform the initial total gDNA quantification and may visualize a subset of your samples on the Agilent TapeStation platform.

For RNA samples, we will perform a total RNA quantification. If you have ordered our RNA clean-up, we will perform a DNase treatment, a bead-based purification, a visualization via Agilent TapeStation, and a second total RNA quantification.

For pre-made libraries, we will perform a total gDNA quantification as well as a qPCR-based assay for properly adapted Illumina-compatible library molecules.

If you order QC-only services, the “Standard QC” is the same as the Standard DNA quality QC above. The “Extended QC” is the same as the Degraded DNA quality QC.

We will provide a QC report with the results of our QC to you when you send us DNA, RNA, or libraries. We will also perform the appropriate QC and send the QC report for samples for which we perform the DNA/RNA extraction.