Tag Archive for: NGS

Ann Arbor, MI

– Swift Biosciences and Daicel Arbor Biosciences, a division of Chiral Technologies, jointly announced a partnership to offer a complete workflow for RNA-Seq library preparation and targeted enrichment of the SARS-CoV-2 genome. An enabling offering for epidemiological research and public health surveillance, the partnership leverages Swift’s patented Adaptase® technology within the Swift RNA Library Kits combined with myBaits technology from Daicel Arbor Biosciences for hybridization-based target enrichment of the virus for whole genome sequencing.

“We are very pleased to partner with our local colleagues in Ann Arbor, to synergize Swift’s library prep technology with Arbor’s myBaits capture technology”, said Drew McUsic, Ph.D., Swift’s Director of Product Management. “As research and public health labs continue to study mutation profiles of the virus across thousands of collected specimens, our collaboration puts a high performing NGS workflow in their hands to efficiently prepare samples for analysis, even when heavily degraded or otherwise incompatible with PCR-based approaches.”

Hybridization-based target enrichment can retrieve target sequences that have significant genomic rearrangements or mutations relative to the reference used for probe or primer design. This allows the Swift and Arbor workflow to be robust to structural nucleotide variants segregating within the SARS-CoV-2 population.

“We have been providing the SARS-CoV-2 panel free of charge to research labs studying the evolution of the novel coronavirus and are excited to partner with Swift Biosciences on this effort,” stated Alison Devault, Director of Genomics at Daicel Arbor Biosciences. “Detection of viral mutations is heavily reliant on sample preparation prior to sequencing and Swift’s RNA library prep meets the sensitivity required for this virus.”

The two companies’ combined product offering includes modules for RNA fragmentation and reverse transcription, library preparation and amplification, indexed adapters, capture probes, blockers, and wash buffers for SARS-CoV-2 enrichment. No ribosomal RNA depletion or other enrichment or depletion steps are required. Customers in North America may purchase the full set of reagents directly from either Swift or from Daicel Arbor Biosciences.

About Swift Biosciences

Swift Biosciences, based in Ann Arbor, Michigan, develops enabling technologies for genomics, translational and clinical research. Swift’s technologies expand the range of sample inputs to broaden applications of next-generation sequencing (NGS). The company has developed unique intellectual property (IP) to enhance adapter ligation to both single and double-stranded DNA, improve multiplexed PCR for targeted sequencing, and enable novel solutions for NGS workflows. Swift’s new RNA Library Kits are the fastest on the market and powered by Swift’s Adaptase® technology, which allows stranded RNA library construction directly from first-strand cDNA.

Swift’s portfolio enables new applications in multiple industries, including agrigenomics, pharmaceutical, academic, biotechnology, and oncology research fields. All products are for research use only. For more information, visit and follow Swift Biosciences on Twitter (@SwiftBioSci).

About Daicel Arbor Biosciences

Daicel Arbor Biosciences, a subsidiary of Chiral Technologies, Inc. (part of Daicel Corporation), is a development and manufacturing company founded by scientists to serve our peers in molecular biology applications. We are a passionate organization of scientists determined to deliver cost-effective, user-friendly products to researchers of genetics and synthetic biology. The team at Daicel Arbor Biosciences prides themselves on providing exceptional customer service and timely technical support to new or advanced users on our array of products. We routinely collaborate with our customers and research partners to develop innovative solutions to address their unique applications. For more information, visit http://www.arborbiosci.com/ and follow Daicel Arbor Biosciences on Twitter (@ArborBio).

Download a pdf of the press release.

For more information on Daicel Arbor Biosciences, contact:

Michele Gentile

Daicel Arbor Biosciences

For more information, contact:

Camille Cappello
Swift Biosciences
cappello@swiftbio.com

Wednesday, March 25, 2020 11:00 AM – 12:00 PM EDT

 

Summary

Even as sequencing costs decline, high-depth sequencing of the 7-17 Gbp wheat genome remains cost-prohibitive.  With the myBaits Expert Wheat Exome Panel, Daicel Arbor Biosciences provides the wheat research and breeding community a simple tool that reduces focused sequencing of the wheat high-confidence exome by more than an order of magnitude compared to whole genome sequencing. Based on the IWGSC RefSeq v1.0 reference genome, with a total target space of >200Mb, this is the most up-to-date panel currently available on the market for complete wheat exome sequencing.

In this webinar, Dr. Jacob Enk (R&D Manager for NGS at Daicel Arbor Biosciences) will present the latest performance developments of the Wheat Exome Panel, including its utility for hexaploid, tetraploid, and diploid cultivars of wheat, as well as upcoming complementary tools for targeted sequencing of exome-wide promoters and new exons as they are continually updated in RefSeq.

The myBaits Expert Wheat Exome Panel is available for immediate shipment from Daicel Arbor Biosciences, and can also be purchased as part of full-service NGS packages for library preparation, enrichment, sequencing and bioinformatics analysis. IWGSC members receive special discounted rates on all Wheat Exome kits and services.

Present by:

Dr. Jacob Enk
NGS R&D Manager
Daicel Arbor Biosciences

[ab_button text=”Register Here” link=”https://register.gotowebinar.com/register/1301270217479890445″]

Ann Arbor, MI

Daicel Arbor Biosciences, a division of Chiral Technologies, Inc. and leader in developing molecular biology research tools, today announced the release of a myBaits Expert hybridization-based panel for the 2019 Novel Coronavirus (2019-nCoV). The next-generation sequencing panel is for research use only, and will be offered free of charge to global researchers working to help identify the source organism and evolution of the virus.

Leveraging their expertise in designing and manufacturing high performance NGS enrichment panels for pathogens, Daicel Arbor Biosciences produced the new 2019-nCoV panel in just one week following a request from the research community. To aid in urgent research on this global threat, Arbor will provide complete 2019-nCoV hybridization capture kits free of charge to researchers worldwide who are studying the epidemiological and phylogenetic properties of this novel virus.

“After receiving the initial request for a 2019-nCoV panel, the urgency of the situation made it clear that we should make comprehensive study kits available as quickly as possible to all members of the virology research community”, stated Alison Devault, Director of Genomics at Daicel Arbor Biosciences. “As agencies work to contain the spread of the virus, the Arbor team is honored to provide any resources that we can to aid researchers in studying the evolution of this new pathogen. Our thoughts continue to be with all the healthcare workers, researchers, and victims of the tragic COVID-19 outbreak.”

The myBaits Expert 2019-nCoV panel is based on all full and partial genome sequences available in the NCBI database as of January 31, 2020. Arbor is actively accepting requests for the panel, which is available for immediate shipment, on their website and through email.

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About Daicel Arbor Biosciences

Daicel Arbor Biosciences, a subsidiary of Chiral Technologies, Inc. (part of Daicel Corporation), is a development and manufacturing company founded by scientists to serve our peers in molecular biology applications. We are a passionate organization of scientists determined to deliver cost-effective, user-friendly products to researchers of genetics and synthetic biology. The team at Daicel Arbor Biosciences prides themselves on providing exceptional customer service and timely technical support to new or advanced users on our array of products. We routinely collaborate with our customers and research partners to develop innovative solutions to address their unique applications.

Contact for Daicel Arbor Biosciences:
Michele Gentile
mgentile@arbor.daicel.com

LGC Biosearch Logo       

Ann Arbor, MI

Daicel Arbor Biosciences, a division of Chiral Technologies, Inc. and worldwide leader in next generation sequencing (NGS) target enrichment, today announced a partnership with Biosearch Technologies, the complete genomics portfolio of LGC Group. LGC Group was founded over 175 years ago, and today supplies products and services in the life sciences sector to improve human healthcare, agri-food technology, and the environment across the world. Together, the organizations will use their extensive resources for genetic testing and marker discovery to deliver custom sequencing solutions to the agrigenomics market.

Through the partnership, Biosearch Technologies will become the exclusive global provider of custom hybridization-based targeted sequencing oligonucleotide panels powered by myBaits technology to commercial agricultural organizations and seed breeding companies. Daicel Arbor Biosciences will maintain their strong presence in academic and government research laboratories by continuing to serve these researchers with catalog and custom panels. Overall, the partnership will allow Biosearch Technologies to leverage their established relationships with commercial organizations by delivering a complimentary technology necessary for marker discovery in crop sciences.

Alison Devault, Director of Genomics at Daicel Arbor Biosciences stated “Custom hybridization capture kits for targeted NGS have been our speciality for almost a decade, and perfectly complement LGC Biosearch’s robust expertise with genotyping assays for commercial ag-bio applications. We are truly excited for this partnership that will allow both parties to better serve key clients and provide innovative, complete NGS solutions for the entire ag-bio genomics market.”

Mark Dearden, VP of Strategy and Marketing at LGC, Biosearch Technologies commented “The addition of custom hybridization-based targeted sequencing panels to our portfolio adds a critical component to our NGS offering for the AgBio sector..  We are excited about taking this next step with Daicel Arbor Biosciences and will continue to invest to support our customer’s  mission critical applications.”

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About Daicel Arbor Biosciences

Daicel Arbor Biosciences, a division of Chiral Technologies, Inc. and a subsidiary of Daicel Corporation, is a development and manufacturing company founded by scientists to serve our peers in molecular biology applications. We are a passionate organization of scientists determined to deliver cost-effective, user-friendly products to researchers of genetics and synthetic biology. The team at Daicel Arbor Biosciences prides themselves on providing exceptional customer service and timely technical support to new or advanced users on our array of products. We routinely collaborate with our customers and research partners to develop innovative solutions to address their unique applications.

About LGC Biosearch Technologies

LGC is an international leader in the extended life sciences sector, including human healthcare, agri-food & the environment. LGC provides a comprehensive range of reference materials, proficiency testing schemes, and genomics reagents​, as well as research and measurement services. Its scientific tools and solutions enable organisations to advance research, develop new products and form an essential part of their quality and compliance procedures.

LGC’s 3,150 employees include internationally-recognised scientists who are experts in their field. Headquartered in London, it operates out of 19 countries worldwide and is extensively accredited to quality standards such as GMP, GLP, ISO 13485, ISO 17034, ISO 17043, ISO/IEC 17025 and ISO 9001.

LGC has been home to the UK Government Chemist for more than 100 years and is the UK National Measurement Laboratory and Designated Institute for chemical and bio measurement. LGC has been privately-owned since 1996 and has diversified through internal investment and acquisition to be an international leader in its chosen markets. LGC is now owned by funds affiliated with KKR.

For more information, please visit www.lgcgroup.com

Contact for Daicel Arbor Biosciences:
Michele Gentile
Daicel Arbor Biosciences

Contact for LGC, Biosearch Technologies:
Julian Quigley
LGC
Julian.quigley@lgcgroup.com
+44 20 8943 8491

Curio Logo

San Diego, California

Arbor Bioscience and Curio Genomics announced an exciting expansion of their existing partnership today at the 28th International Plant and Animal Genome conference in San Diego. The enhanced partnership promises to deliver a host of additional first-in-class products and solutions to the plant research and development community in commercial, as well as, non-profit foundations, consortia, and academic institutions.

With a potential deal value exceeding $1 million, the multiyear partnership leverages the core expertise and experience of each company to deliver cutting-edge, robust and comprehensive products for customers. Daicel Arbor Biosciences brings decades of combined expertise in NGS with novel advanced synthesis chemistry and expert scientific consulting to develop both catalog and custom targeted sequencing panels. Curio Genomics brings decades of experience in big-data commercial software platforms designed from the beginning for limitless scalability and extensibility, essential for genomic research with larger data sets, new types, and greater demand to integrative analyses each year.

“This is a transformative partnership for Curio,” said David Brabec, Curio’s Chief Business Officer. “We know that researchers, both commercial and academic, want and need solutions that are continuously cutting-edge, if we are going to continue feeding a growing world in a time when our climate is rapidly changing. Daicel Arbor Biosciences’ decades of combined scientific expertise in NGS and their track record of delighted customers was a key for us choosing them as our first major partner.”

“Curio is the perfect partner as we continue to expand Arbor’s solutions to enhance and simplify research for our customers,” said Arbor Bioscience’s Director of Genomics, Alison Devault. “The plant genomics space is an incredibly exciting business opportunity, but also a truly meaningful research space for translational and social impact. We are proud to be making such a visible commitment to this important and adapting market.”

Product Roadmap

The companies’ announcement included immediate plans to expand their existing and acclaimed wheat exome and complete genome analysis solution by fully integrating their current offerings by mid-2020 with new capabilities for wheat researchers, such assupport for RNA-Seq and methylation analysis, to be released later in 2020, and over the course of the multiyear partnership. The companies also announced immediate plans to co-develop products for additional species beyond wheat and will disclose these product plans at a later date.

“With Arbor’s decades of combined experience in NGS, we will leverage the power of the Curio® platform to provide whole genomic research teams a collaborative and endlessly extensible environment for real-time processing, analysis and interpretation of plant genomic data,” said Curio’s co-founder and CTO, Shawn Quinn. “We are excited to provide complete solutions for researchers from question to sample to insight and back again.”

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About Daicel Arbor Biosciences, Inc.

Daicel Arbor Biosciences, a division of Chiral Technologies, Inc. and a subsidiary of Daicel Corporation, is a development and manufacturing company founded by scientists to serve our peers in molecular biology applications. We are a passionate organization of scientists determined to deliver cost-effective, user-friendly products to researchers of genetics and synthetic biology. The team at Daicel Arbor Biosciences prides themselves on providing exceptional customer service and timely technical support to new or advanced users on our array of products. We routinely collaborate with our customers and research partners to develop innovative solutions to address their unique applications.

About Curio Genomics

Curio Genomics leverages its decades of big data commercial software development experience to provide the robust, rapidly extensible bioinformatics platform called Curio™. The guiding principle of Curio Genomics is that software should facilitate genomic research, not consume it. Through fully integrated partnerships with Next-Gen Sequencing leaders, Curio provides powerful, first-in-class product solutions that empower researchers from sample-to-insight. For information about Curio Genomics unique bioinformatics software platform, visit www.curiogenomics.com

Contact for Daicel Arbor Biosciences:

Michele Gentile
mgentile@arbor.daicel.com

Contact for Curio Genomics:

David Brabec
Curio Genomics
dbrabec@moxiegenomics.com
+1 734 726 7581