Yes! A full AVITI flowcell generates approximately 240Gbp of PE150 data.

If you need more data and need it speedily, the AVITI can run two flowcells simultaneously.

Yes! We can offer AVITI sequencing in units of Gbp, which is ~3.3M PE150 read pairs. The price per Gbp goes down the more Gbp you get!

You’ll receive demultiplexed, but otherwise raw FASTQ files. There will be two files (read 1 and read 2) per sample. If you are familiar with Illumina sequencing output, the data will be identical to the format you are familiar with.

  • Decreased sequencing turnaround time. With the sequencer in Arbor’s hands, we’re in full control of the speed and can provide data at least 2 weeks faster than ever before.
  • Increased read quality. Runs frequently produce results with >90% of reads meeting or exceeding Q30 quality scores. 
  • Flexibility. Mid-sized flowcells (~240Gbp) make flowcell-level pricing accessible for smaller project sizes.
  • Compatibility. The AVITI is compatible with all of Arbor’s existing short-read library preparation (and capture) options, so you can feel confident knowing that your precious samples will be handled with the protocols you trust. 

While the output (FASTQ files) is the same, the sequencing chemistry is different. The AVITI uses “avidity sequencing,” which is a sequencing-by binding chemistry. Illumina sequencing employs a sequencing-by synthesis chemistry. The avidity sequencing chemistry improves the accuracy of the basecalls. Read more about avidity sequencing here.

AVITI is the new short-read medium-throughput sequencing platform from Element Biosciences. It is a drop-in replacement for Illumina sequencers – meaning that it is compatible with Illumina libraries and the data format is the same as you’d get with an Illumina sequencer.

Many sample types and species will require special permits for shipping internationally (or domestically). We can provide some advice, but ultimately you are responsible for proactively identifying the permit(s) that are required for your unique samples. Some examples of biological samples that require permits are tissue or DNA from CITES-listed specimens and plant tissues regulated by the USDA/APHIS.

If Daicel Arbor Biosciences is required to apply for an import permit on your behalf, you will be required to pay a permit application fee, regardless of whether the application is successful.

We strongly encourage our customers to research shipping regulations before contacting us about your project to determine your specific permit needs. Incorrect or incomplete documentation may result in the seizure and loss of your samples at Customs, and potentially the assignment of fines/fees.

Yes. We require documentation that all relevant and necessary ethics approvals have been granted for any human specimens that you would like us to work on. This includes both contemporary and ancient samples and includes both tissue and nucleic acid derivatives. Please contact us to receive our Ethics Statement document if you are interested in sending human samples to us. We do not accept clinical specimens and are not CLIA-certified.

We prepare short-insert libraries with 8-bp unique dual indexes.

We prepare long-insert libraries with 16 bp identical dual indexes.

Our library preparation protocols have been carefully tested and optimized for both WGS and targeted sequencing applications. We have protocols that are appropriate for a wide range and variety of input qualities and quantities that have been successfully applied to thousands of samples. Therefore it is very likely that one of our existing protocols will work well for your application, but if you have very specific project constraints, our NGS experts would be happy to discuss the options with you.